{"id":39699,"date":"2025-01-03T16:29:27","date_gmt":"2025-01-03T16:29:27","guid":{"rendered":"https:\/\/paleyinstitute.org\/?page_id=39699"},"modified":"2025-06-17T14:33:59","modified_gmt":"2025-06-17T14:33:59","slug":"neurofibromatosis-1-nf1","status":"publish","type":"page","link":"https:\/\/paleyinstitute.org\/neurofibromatosis-1-nf1\/","title":{"rendered":"Neurofibromatosis 1 (NF1)"},"content":{"rendered":"\t\t
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Neurofibromatosis 1 (NF1)<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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NF1 is a genetic disorder that affects the growth and development of cells in the body. It is characterized by the growth of tumors along the nerves in the body, as well as other symptoms such as skin discoloration, bone abnormalities, and learning disabilities. The condition is caused by a mutation in the NF1 gene, which helps regulate cell growth and division. There is no cure for NF1, but treatments are available to manage the symptoms and prevent complications. Our team is highly experienced in treating children with NF1 who have orthopedic and neurologic manifestations. Our physicians have treated more than 500 kids with NF1.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Explained for Kids<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Imagine our body is like a beautiful jungle full of amazing animals! Well, in NF1, sometimes our jungle friends might have spots on their fur. Kids with NF1 might have spots on their skin, kind of like the spots you see on a leopard or a cheetah! These spots are called “caf\u00e9-au-lait spots” and they’re like little marks that make them unique. Sometimes, they might even have little bumps or lumps under their skin, like tiny surprises hiding in the jungle.<\/span><\/p>

But don’t worry! Just like the wise old elephants and strong lions, doctors are here to help! They have special tools and magic tricks to keep our jungle friends healthy and happy. They’ll watch over these spots and bumps to make sure they’re not causing any trouble. And if they need to, they’ll use their special powers to help fix things up.<\/span><\/p>

With their help, kids with NF1 can still explore the jungle and have amazing adventures, just like any other kid! Remember, even though our bodies might have different spots, we’re all part of this wild and wonderful jungle together! \ud83d\ude0a\ud83d\udc3e\ud83c\udf3f<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Explained for Parents<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Neurofibromatosis Type 1 (NF1) is a genetic disorder caused by mutations in the NF1 gene, leading to abnormal cell growth and the development of tumors along nerves in the body. These tumors, known as neurofibromas, can occur anywhere in the body, including the skin, brain, and spinal cord. NF1 is characterized by a wide range of symptoms, which can vary greatly among affected individuals. The most common signs include caf\u00e9-au-lait spots, which are flat, light brown patches on the skin, and neurofibromas, which appear as soft, fleshy bumps under the skin. Other features may include freckling in areas such as the armpits and groin, Lisch nodules (nodules on the iris of the eye), bone abnormalities such as scoliosis or thinning of the long bones, and learning disabilities or cognitive impairments.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Diagnosis of NF1 is typically based on clinical criteria which include the presence of specific characteristic features, such as caf\u00e9-au-lait spots and neurofibromas. Genetic testing may also be recommended to confirm the diagnosis, particularly in cases where the clinical presentation is atypical. While there is currently no cure for NF1, treatment aims to manage symptoms and complications associated with the disorder. This may involve regular monitoring by healthcare providers to assess for tumor growth and complications, such as vision problems or skeletal abnormalities. Surgical removal of tumors may be necessary in some cases, and other interventions, such as physical therapy or educational support, may be recommended to address associated symptoms or disabilities.<\/span><\/p>

The prognosis for individuals with NF1 varies widely depending on the severity and progression of symptoms. While NF1 is generally not life-threatening, it can significantly impact quality of life and may require lifelong medical management and support. Regular follow-up with healthcare providers is essential to monitor for potential complications and provide appropriate care.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Paley Institute Doctors who specialize in NF1 in West Palm Beach & Jupiter<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\tDr. Kaveh Asadi\t\t\t\t\t<\/h1>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t
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\n\t\t\t\t\t\tDr. Craig Robbins\t\t\t\t\t<\/h1>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t
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\n\t\t\t\t\t\tDr. Katherine Miller\t\t\t\t\t<\/h1>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t
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\n\t\t\t\t\t\tDr. Claire Shannon\t\t\t\t\t<\/h1>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t
\n\t\t\t\t\t\tPediatric Orthopedic Surgeon\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t
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Neurofibromatosis 1 (NF1) NF1 is a genetic disorder that affects the growth and development of cells in the body. It is characterized by the growth of tumors along the nerves in the body, as well as other symptoms such as skin discoloration, bone abnormalities, and learning disabilities. The condition is caused by a mutation in the NF1 gene, which helps regulate cell growth and division. There is no cure for NF1, but treatments are available to manage the symptoms and prevent complications. Our team is highly experienced in treating children with NF1 who have orthopedic and neurologic manifestations. Our physicians have treated more than 500 kids with NF1. Explained for Kids Imagine our body is like a beautiful jungle full of amazing animals! Well, in NF1, sometimes our jungle friends might have spots on their fur. Kids with NF1 might have spots on their skin, kind of like the spots you see on a leopard or a cheetah! These spots are called “caf\u00e9-au-lait spots” and they’re like little marks that make them unique. Sometimes, they might even have little bumps or lumps under their skin, like tiny surprises hiding in the jungle. But don’t worry! Just like the wise old elephants and strong lions, doctors are here to help! They have special tools and magic tricks to keep our jungle friends healthy and happy. They’ll watch over these spots and bumps to make sure they’re not causing any trouble. And if they need to, they’ll use their special powers to help fix things up. With their help, kids with NF1 can still explore the jungle and have amazing adventures, just like any other kid! Remember, even though our bodies might have different spots, we’re all part of this wild and wonderful jungle together! \ud83d\ude0a\ud83d\udc3e\ud83c\udf3f Explained for Parents Neurofibromatosis Type 1 (NF1) is a genetic disorder caused by mutations in the NF1 gene, leading to abnormal cell growth and the development of tumors along nerves in the body. These tumors, known as neurofibromas, can occur anywhere in the body, including the skin, brain, and spinal cord. NF1 is characterized by a wide range of symptoms, which can vary greatly among affected individuals. The most common signs include caf\u00e9-au-lait spots, which are flat, light brown patches on the skin, and neurofibromas, which appear as soft, fleshy bumps under the skin. Other features may include freckling in areas such as the armpits and groin, Lisch nodules (nodules on the iris of the eye), bone abnormalities such as scoliosis or thinning of the long bones, and learning disabilities or cognitive impairments. Diagnosis of NF1 is typically based on clinical criteria which include the presence of specific characteristic features, such as caf\u00e9-au-lait spots and neurofibromas. Genetic testing may also be recommended to confirm the diagnosis, particularly in cases where the clinical presentation is atypical. While there is currently no cure for NF1, treatment aims to manage symptoms and complications associated with the disorder. This may involve regular monitoring by healthcare providers to assess for tumor growth and complications, such as vision problems or skeletal abnormalities. Surgical removal of tumors may be necessary in some cases, and other interventions, such as physical therapy or educational support, may be recommended to address associated symptoms or disabilities. The prognosis for individuals with NF1 varies widely depending on the severity and progression of symptoms. While NF1 is generally not life-threatening, it can significantly impact quality of life and may require lifelong medical management and support. Regular follow-up with healthcare providers is essential to monitor for potential complications and provide appropriate care. Paley Institute Doctors who specialize in NF1 in West Palm Beach & Jupiter Dr. Kaveh Asadi Pediatric Neurosurgeon Schedule an Appointment Dr. Craig Robbins Orthopedic Surgeon Schedule an Appointment Dr. Katherine Miller Pediatric Orthopedic Surgeon Schedule an Appointment Dr. Claire Shannon Pediatric Orthopedic Surgeon Schedule an Appointment<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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